Swedish 3D bioprinter and materials developer CELLINK has entered the microscopy sector. Addressing one of the most vital peripheral activities to studying cell cultures, the company has launched...
Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use. The production of these antibiotics—used by the bacteria to fend off...
The new method developed by Wakonig and his colleagues circumvents this problem. "The final image is as if we had measured with a large lens," the researcher explains.
A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive...
So far, many optical microscopies such as phase contrast microscopy, fluorescence microscopy, multi-photon microscopy, and super-resolved fluorescence microscopy have been developed.
A new optical microscope system called stimulation and imaging-based functional optical microscopy (SIFOM) can stimulate multiple cells simultaneously via a holographic method and monitor cell...
Two newly developed methods will help researchers to study the 3-D structure of complex surfaces and of individual neurons better than ever before. Sebastian Munck and Natalia Gunko, two expert...
The biotech R&D sector is thriving in Flanders, and this is in no small part due to presence of a lot of tech development and know-how, enabling scientists to carve out a path towards new...
Optoacoustic imaging powered by short bursts of continuous wave (CW) lasers can stimulate the emission of ultrasound waves inside an animal or in human subjects.
Finding defects in electron microscopy images takes months. Now, there's a faster way. It's called MENNDL, the Multinode Evolutionary Neural Networks for Deep Learning.
Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular...
Going deeper and deeper into cells with the microscope; imaging the nucleus and other structures more and more accurately; getting the most detailed views of cellular multi-protein complexes: All of...
At the Vienna University of Technology, a clearing method has now been developed that can be applied to insects, which is a particularly difficult task. With an improved light-sheet microscope (a...
The transporter protein ABCG2 belongs to the ATP-binding-cassette (ABC) family. The protein is expressed in the plasma membranes of cells within a variety of tissues and tissue barriers, including...
Microscopes make the invisible visible. And compared to conventional light microscopes, transmission x-ray microscopes (TXM) can see into samples with much higher resolution, revealing extraordinary...
The molecule, called transcription factor IID, is critical to transcribing genes into RNA that will later be used as blueprints to make proteins. Because of its many moving parts and large size,...
Comparison between 2P- and 3P-LSFM. Axial maximum intensity projections of 3D stacks of images of 1 μm blue fluorescing microspheres embedded in agarose under (a) 2P excitation at 700 nm and (b) 3P...
A novel technique that nudges single atoms to switch places within an atomically thin material could bring scientists another step closer to realizing theoretical physicist Richard Feynman's vision...
Notorious asphyxiator carbon monoxide has few true admirers, but it's favored by University of California, Irvine scientists who use it to study other molecules.
Super-resolution microscopy is a technique that allows researchers to see beyond the diffraction limit of light. The technique has garnered increasing interest, especially since its developers won...
The field of optical microscopy research has developed rapidly in recent years. Thanks to the invention of a technique called super-resolution fluorescence microscopy, it has recently become...
Careful sample preparation, electron tomography and quantitative analysis of 3-D models provides unique insights into the inner structure of reverse osmosis membranes widely used for salt water...
These reverse osmosis membranes are layers of material with an active aromatic polyamide layer that allows water molecules through, but screens out 99 to 99.9 percent of the salt.
"It's not an overstatement to say that this is one of the best cryo-EM structures that's ever been achieved in this field," says Salk Assistant Professor Dmitry Lyumkis, a structural biologist and...
Ralf Jungmann is interested in processes that take place within spatial dimensions that are unbelievably tiny. Jungmann holds a professorship in Experimental Physics at...
"What we were able to see for the first time is that lithium peroxide develops in the liquid electrolyte of lithium-oxygen batteries, and is a contributor to the slow down and ultimate death of these...
A new microscopy technique allows researchers to track microstructural changes in real time, even when a material is exposed to extreme heat and stress. Recently, researchers show that a stainless...
Jan Huisken, a medical engineering investigator at the Morgridge Institute for Research and co-founder of light sheet microscopy, has a new project meant to bridge the technology gap.
A novel technique developed by researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) will help shine new light on biological questions by improving the quality and quantity...
Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix (ECM), a collection of molecules surrounding the cells that provide...
A material with atomically thin layers of water holds promise for energy storage technologies, and researchers have now discovered that the water is performing a different role than anyone...
Physicists from Dresden and Würzburg have developed a novel method for optical microscopy, obtaining high-resolution images using biological motors and single quantum dots.
For this reason, scientists worldwide have developed elaborate concepts in the past in order to circumvent the diffraction limit and thus to increase the resolution.
The collaborating institutions include the EMSL, the Environmental Molecular Sciences Laboratory, a Department of Energy Office of Science User Facility at the Pacific Northwest National Laboratory...
It is one of the most accurate measurement instruments available today: the high-performance microscope at the Institute of Applied Physics of TU Wien acquires images of individual atoms by moving...
The herpesvirus is genetically and structurally one of the most complex viruses. It spreads within the host population efficiently, causing a range of diseases in humans, including congenital...
Scientists have a better understanding of a mechanism that allows cells to internalize beneficial nutrients and not-so-beneficial viruses, thanks to collaboration among researchers from two South...
Called COSMIC, for Coherent Scattering and Microscopy, this X-ray beamline at Berkeley Lab's Berkeley Lab's Advanced Light Source (ALS) allows scientists to probe working batteries and other active...
A next-generation X-ray beamline now operating at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) brings together a unique set of capabilities to measure the...
Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein. With the help of cryo-electron microscopy...
A University of Texas at Dallas graduate student, his advisor and industry collaborators believe they have addressed a long-standing problem troubling scientists and engineers for more than 35...
University of Groningen microbiologists have visualized tiny islands in the cell membrane of baker's yeast. These membrane compartments appear to store transport proteins before use.
One of today's sharpest imaging tools, super-resolution microscopy, produces sparkling images of what until now has been the blurry interior of cells, detailing not only the cell's internal organs...
A team of researchers from ICMAB has proved that unconventional AFM probes are suitable for acquiring a true piezoelectric signal in piezoresponse force microscopy.
Staff members at King Abdullah University of Science and Technology (KAUST) have devised a methodology for the procurement of atomically resolved images of beam-sensitive materials using...
UC San Francisco researchers recently captured exquisite images of a protein caught in the act of binding to a novel therapeutic drug with enough resolution to model how the individual atoms of the...
A team of researchers at Cornell University has developed a way to dramatically improve the resolution of confocal microscopy. They describe the technique in a paper they have had published in...
Nobel Prize in Chemistry goes to two American researchers, one Swiss. "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution" Images -...
Jacques Dubochet, Joachim Frank and Richard Henderson have claimed this year's Nobel Prize in Chemistry. The trio earned the prize for their work on cryo-electron microscopy, which is an imaging...
WASHINGTON— Jacques Dubochet, Joachim Frank and Richard Henderson have claimed this year’s Nobel Prize in Chemistry. The trio earned the prize for their work on cryo-electron microscopy, which is...