Unexpected connection between gliomas, neurodegenerative diseases

ScienceDaily | 1/23/2020 | Staff
srqlolosrqlolo (Posted by) Level 3
The new study, in mouse models and human brain tumor tissues, was published in Science Translational Medicine and found a significant expression of the protein TAU in glioma cells, especially in those patients with better prognoses.

Patients with glioma are given a better prognosis when their tumor expresses a mutation in a gene called isocitrate dehydrogenase 1 (IDH1). In this international collaborative study led by the Instituto de Salud Carlos III-UFIEC in Madrid, Spain, those IDHI mutations stimulated the expression of TAU. Then, the presence of TAU acted as a brake for the formation of new blood...
(Excerpt) Read more at: ScienceDaily
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