Low doses of radiation used in medical imaging lead to mutations in cell cultures

ScienceDaily | 1/16/2020 | Staff
liizuliizu (Posted by) Level 3
Scientists have long known that exposing cells to high doses of ionizing radiation generates mutations by creating double-strand breaks that let in external segments of DNA. These extraneous fragments of DNA can occur in the nucleus, left over from natural processes, such as genomic DNA repair and viral infections. In the new study, researchers investigated whether low doses of ionizing radiation have damaging side effects by irradiating human and mouse cells grown in the lab. When they counted the cells that had taken up foreign DNA, they found that low doses of radiation, in the upper range of common diagnostic procedures, create mutations through inserted DNA even more efficiently than the much larger doses studied previously.

While the new results in cell cultures are potentially concerning, the study's authors stress that translating radiation's effects on lab-grown cell cultures to effects in the body is premature. Future experiments using animal models will be...
(Excerpt) Read more at: ScienceDaily
Wake Up To Breaking News!
Sign In or Register to comment.

Welcome to Long Room!

Where The World Finds Its News!