The modified red blood cells are designed to circulate in the body for several weeks at a time, seeking out specific targets including bacteria, tumours or organs.
The technology, described in the online edition of the journal Advanced Biosystems, solves a major problem with current drug delivery methods that use synthetic molecules and cannot reach specific targets or are rejected by the body.
Blood - Cells - Stealth - Drug - Carriers
"We call these super-human red blood cells. We think that they could work as the perfect stealth drug carriers which can outsmart our immune system," explains Maikel Rheinstädter, a senior advisor on the study and professor in the Department of Physics & Astronomy at McMaster.
The researchers have developed a method to open up the red blood cell, modify its outer cell wall, and replace its contents with a drug molecule, which would...
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