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Scientists at the Far Eastern Federal University (FEFU) and the G.B. Elyakov Pacific Institute of Bioorganic Chemistry (FEB RAS) together with German colleagues spotted six new and three already known biologically active compounds in a new strain of the fungus Penicillium piltunensein the first time it has been isolated. One compound has a pronounced anti-inflammatory activity, others have herbicidal potential, i.e., they can possibly become components of new chemicals for weed control. A related study is published in Marine Drugs.
The spotted compounds are the derivatives of aspterric acid, from which herbicidal activity was previously highlighted in a scientific report published in Nature journal. The authors of the report noted that the acid has a moderate ability to inhibit plant growth, but suggested its analogs may be more effective.
Compounds - Herbicidal - Activity - Analogs - Acid
"We believe that the compounds isolated could potentially have herbicidal activity since they are the very analogs of aspterric acid, which our foreign colleagues wrote about in Nature. We have not yet been able to check how strongly these properties are expressed in the substances found, but we plan to find it out further. Worth noting—new herbicidal compounds have not been introduced onto the market for about 30 years," said Olesya Zhuravleva, Ph.D., Head of the Laboratory...
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