"Asthma is a tremendously variable disease," said Michael Wechsler, MD, professor of medicine at National Jewish Health and first author on the study published in the New England Journal of Medicine. "We need to more closely study subgroups of asthma patients, especially those disproportionately burdened by disease, such as African Americans."
The researchers evaluated 280 children, ages 5-11, and 294 adolescents/adults of African American ancestry whose asthma was inadequately controlled with low doses of inhaled corticosteroids. Treatment guidelines call for adding a long-acting beta agonist as the preferred step-up therapy. Researchers several medication strategies -- adding long-acting beta agonists, increasing inhaled steroids alone and both increasing inhaled steroids and adding long-acting beta agonists.
Researchers - Response - Factors - Exacerbations - Asthma
The researchers measured response by evaluating several factors including exacerbations, asthma control days and lung function.
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