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Biopharmaceuticals are necessary, life-saving tools. But the process for making them is time-consuming and costly, particularly when it comes to the process of purification—the removal of unwanted elements like proteins, viruses, and DNA.
A team of chemical and biological engineers at Rensselaer Polytechnic Institute has developed a method that significantly cuts down the amount of time needed for the purification process, laying the groundwork for faster, less expensive drug production. The findings were recently published in Biotechnology and Bioengineering, where the article was named an editor's choice.
Technologies - Processes - Modeling - Techniques - Engineering
"We're developing new technologies, new processes, and new modeling techniques for more efficient engineering processes for making drugs," said Steven Cramer, an endowed chair professor of chemical and biological engineering at Rensselaer who led this research.
Choosing which purification process to use on a biopharmaceutical is known as the process development phase. In this paper, Cramer and his team show that they can cut down the amount of time that process takes from months to...
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