Cardiovascular Disease (CVD) remains the leading cause of mortality among middle aged adults globally, accounting for 40% of all deaths, but this is no longer the case in HIC, where cancer is now responsible for twice as many deaths as CVD, according to a new report  from the PURE study published in The Lancet and presented at the ESC Congress 2019. It was estimated that 55 million deaths occurred in the world in 2017, of which approximately 17·7 million were due to cardiovascular disease (CVD).
The PURE study is the only large prospective international cohort study that involves substantial data from a large number of MIC and LIC, as well as HIC, and employs standardised and concurrent methods of sampling, measurement and follow-up.
Report - Adults - % - Women - HIC
The first report, which followed 162,534 middle-aged adults (aged 35 -- 70, 58% women) in 4 HIC, 12 MIC and 5 LIC over a median of 9.5 years (between 2005 -- 2016), found that CVD related deaths were 2.5 times more common in middle-aged adults in LIC compared with in HIC, despite LIC experiencing a substantially lower burden of CVD risk factors compared with wealthier countries. Authors suggested that higher CVD related mortality in LIC may be mainly due to lower quality of healthcare, given that the report found first hospitalisation rates and CVD medication use to be both substantially lower in LIC and MIC, compared with in HIC.
"The world is witnessing a new epidemiologic transition among the different categories of non-communicable diseases (NCD), with CVD no longer the leading cause of death in HIC," said Dr. Gilles Dagenais, Emeritus Professor at Laval University, Quebec, Canada and lead author of the first report. "Our report found cancer to be the second most common cause of death globally in 2017, accounting for 26% of all deaths. But as CVD...
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