How cellular fibers form and maintain dynamic states

phys.org | 7/18/2019 | Staff
jenny1246 (Posted by) Level 3
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Cells assemble dynamically: Their components are continuously exchanging and being replaced. This enables the structures to adapt easily to different situations, and by rearranging the components to respond to stimuli faster, to renew or to form just on demand. The microtubules, a scaffold structure made of protein fibers that can be found in the cytoplasm of the cells of algae, plants, fungi, animals and humans, are one such dynamic mesh.

Because of their self-organizing structure, these fibers constantly form and degrade at the same time, thereby actively supporting the cell in complex tasks such as cell division or locomotion. The fibers require energy to form and maintain such dynamic states. Now, for the first time, Prof. Dr. Andreas Walther and Dr. Laura Heinen from the Institute for Macromolecular Chemistry and the Center of Interactive Materials and Bioinspired Technologies (FIT) at the University of Freiburg have succeeded in programming the dynamics of such dissipative, i.e. energy-consuming, structures in an artificial chemical system on the basis of DNA components. The researchers present their results in the latest edition of the journal Science Advances.

Difficulty - Dynamics - Systems - Synchronization - Deactivation

The difficulty of programmable structural dynamics in synthetic dissipative systems is the synchronization of the energetic deactivation and activation with the structural build-up and degradation...
(Excerpt) Read more at: phys.org
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