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A new expert review highlights the opportunities and methodological challenges at this critical juncture in the growth of the field of metagenomics. With important implications and applications in clinical medicine, public health, biology, and ecology, metagenomics is benefitting from advances in high-throughput techniques and technology, while facing the challenges of big data storage and analysis, according to the review article published in OMICS: A Journal of Integrative Biology, the peer-reviewed interdisciplinary journal published by Mary Ann Liebert, Inc., publishers.
Ilaria Laudadio, Valerio Fulci, Laura Stronati, and Claudia Carissimi, at Sapienza University of Rome, Italy, coauthored the article entitled "Next Generation Metagenomics: Methodological Challenges and Opportunities." Metagenomics provides a view into the genetic composition of microbial communities, whether from environmental, human, or other types of samples. The authors identify the major bottlenecks in current metagenomic experimental design and data reporting and analysis. They discuss the differences in previous shotgun metagenomics...
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