Team discovers control of cell signaling using a cobalt (III)-nitrosyl complex | 4/7/2019 | Staff
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Two professors' joint research team has discovered how to synthesize new materials to deliver nitric oxide, which controls the cell activation signal. The cell signaling control is expected to contribute positively to the development of treatment for cardiovascular diseases.

DGIST announced on June 24 that Professor Jaeheung Cho and Professor Daeha Seo's research teams in the Department of Emerging Materials Science developed a stable cobalt(III)-nitrosyl complex and confirmed the changes of the signal transmission path of nitric oxide inside the cells.

Nitric - Oxide - Controls - Cell - Activities

Nitric oxide controls cell activities by delivering various biochemical information including vasodilation, immune system control, and signal transmission. However, scientists haven't been able to clarify the details concerning nitric oxide delivery to cells due to difficulties in controlling and regulating its movement, although they have assumed nitric oxide movement to cells occurs.

To identify this, the research team synthesized a cobalt(III)-nitrosyl complex on their own, enabling additional research on nitric oxide by shedding light on it and...
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