New compound which kills antibiotic-resistant superbugs discovered

phys.org | 6/27/2018 | Staff
trainman (Posted by) Level 3
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A new compound which visualises and kills antibiotic resistant superbugs has been discovered by scientists at the University of Sheffield and Rutherford Appleton Laboratory (RAL).

The team, led by Professor Jim Thomas, from the University of Sheffield's Department of Chemistry, is testing new compounds developed by his Ph.D. student Kirsty Smitten on antibiotic resistant gram-negative bacteria, including pathogenic E. coli.

Bacteria - Strains - Infections - Pneumonia - Tract

Gram-negative bacteria strains can cause infections including pneumonia, urinary tract infections and bloodstream infections. They are difficult to treat as the cell wall of the bacteria prevents drugs from getting into the microbe.

Antimicrobial resistance is already responsible for 25,000 deaths in the EU each year, and unless this rapidly emerging threat is addressed, it's estimated by 2050 more than 10 million people could die every year due to antibiotic resistant infections.

Doctors - Treatment - Bacteria - Years - Drugs

Doctors have not had a new treatment for gram-negative bacteria in the last 50 years, and no potential drugs have entered clinical trials since 2010.

The new drug compound has a range of exciting opportunities. As Professor Jim Thomas explains: "As the compound is luminescent it glows...
(Excerpt) Read more at: phys.org
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