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Doctors deploy the antibiotic colistin when all other infection-fighting options are exhausted. But resistance to colistin has emerged around the globe, threatening its efficacy.
"This last-resort antibiotic has been designated a highest-priority antibiotic by the United Nations' World Health Organization, and the mcr-9 gene causes bacteria to resist it," said Martin Wiedmann, food safety professor and senior author on the study, published May 7 in the journal mBio. "In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die."
Author - Laura - Carroll - Biologist - Cornell
Co-lead author Laura Carroll, a computational biologist and Cornell doctoral candidate, found mcr-9 in the genome of a strain of foodborne pathogen salmonella.
Mcr-9 is the latest in this new series of "mobilized colistin-resistance" genes -- originally discovered in 2015. The National Center for...
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