One in five men has a gene that makes prostate cancer more deadly

Mail Online | 5/6/2019 | Victoria Allen Science Correspondent For The Daily Mail
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Men with prostate cancer are three times more likely to die from it if they have a particular genetic mutation.

Up to one in five patients may have a genetic quirk which worsens their chances of survival and makes them more likely to relapse.

Men - Prostate - Cancer - Scientists - Cancer

Most men with prostate cancer do not die from it, but scientists sought to find those with advanced cancer who were at greatest risk. In a study of 429 men at this stage of cancer, they found those with a mutated gene called RB1 in their tumour were 3.3 times more likely to die.

The genetic study is the largest ever carried out for advanced prostate cancer and could help doctors identify men with very aggressive cancer and target them with different treatment.

Co-author - Professor - Johann - Bono - Institute

Co-author Professor Johann de Bono of the Institute of Cancer Research in London said: ‘Our study really got under the bonnet of prostate cancer to understand the “engine” driving tumour growth and explore how a range of genes affect the disease and its response to treatment.

Prostate cancer has gained attention lately from actor Stephen Fry and presenter Bill Turnbull talking about their experiences with the disease, while the Daily Mail has long campaigned for improved treatments and diagnosis.

Men - Prostate - Cancer - Die - Question

Only one in 41 men with prostate cancer die from it, raising the question of whether patients’ odds of survival are...
(Excerpt) Read more at: Mail Online
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