Discovery of RNA transfer through royal jelly could aid development of honey bee vaccines | 4/18/2019 | Staff
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Researchers have discovered that honey bees are able to share immunity with other bees and to their offspring in a hive by transmitting RNA 'vaccines' through royal jelly and worker jelly. The jelly is the bee equivalent of mother's milk: a secretion used to provide nutrition to worker and queen bee larvae.

The findings suggest new ways to protect bees against viruses and the deadly Varroa mite that have been responsible for the recent dramatic decline in honey bee populations. Since around one third of the human diet globally is dependent on honey bee pollination, we need solutions urgently to help maintain flourishing bee colonies, for our food security and sustainability.

Dr - Eyal - Maori - Wellcome - Trust/Cancer

Dr. Eyal Maori from the Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, and his collaborators in Israel and the USA had been trialling a new type of antiviral therapy for bees when they got a hint that the bees were able to transmit biologically-active RNA molecules between colony members. The scientists today publish the evidence for such a bee-to-bee RNA transfer phenomenon in the journal Cell Reports.

These transmissible RNA molecules are produced by the honey bee's genes and by disease agents such as viruses. Unlike other RNA in the body, these RNA molecules do not code for protein. Instead, they play a direct role in immunity, gene regulation and other biological mechanisms.

Studies - Dr - Maori - Colleagues - Bees

In previous studies, Dr. Maori and colleagues fed bees with RNA fragments that included a segment of an RNA virus. They found that similar to how vaccines work, the dietary RNA activated an immune response that prevented disease and death when hives were later exposed to the live virus. Intriguingly, the colony maintained a healthy performance for several months after treatment had finished, suggesting that it was still immune to infection—even though the original treated bees would have...
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