Doctors turning to antibiotic alternatives to treat acne

ScienceDaily | 4/24/2019 | Staff
Night987 (Posted by) Level 3
The findings, published as Part I and Part II in the journal Dermatologic Clinics, surveyed studies on acute and long-term acne treatments over the past decade to identify trends.

"People are more conscious about the global health concern posed by the overuse of antibiotics and that acne is an inflammatory, not infectious, condition," said Hilary Baldwin, clinical associate professor of dermatology at Rutgers Robert Wood Johnson Medical School. "Overuse of antibiotics also can promote the growth of resistant bacteria, which can make treating acne more challenging."

Use - Antibiotics - Microbiome - Trillions - Bacteria

Prolonged use of antibiotics can affect the microbiome (the trillions of bacteria, viruses and fungi that inhabit our bodies) in areas other than the skin, resulting in disease. The report noted that people who use topical and oral antibiotics were three times as likely to show an increase of bacteria in the back of their throat and tonsils compared with non-users. Long-term use of antibiotics in acne treatment also is associated with an increase in upper respiratory infections and skin bacteria and was shown to affect a user's blood-sugar level.

However, doctors are increasingly exploring combinations of therapies instead of antibiotics for long-term treatment. Baldwin said there is renewed interest in the antibacterial medication benzoyl peroxide that often is used in combination with topical retinoids, which are medicines derived from vitamin A. One benefit is that benzoyl peroxide, which kills the acne-causing bacteria, helps the skin shed more effectively, reduces clogged pores and does not promote resistant acne-inducing bacteria strains.

Acne - Teens - Adulthood - Women - Report

Although acne is common in teens, it can continue into adulthood, affecting mainly women. The report notes that about 50 percent of women in their 20s, one-third in their 30s and one-quarter in their 40s suffer from the condition. The oral medication spironolactone is particularly effective in women. Although this medication, which is...
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