DNA is managed like climbers' rope to help keep tangles at bay

ScienceDaily | 4/22/2019 | Staff
chrismpotts (Posted by) Level 3
Click For Photo: https://www.sciencedaily.com/images/2019/04/190422100945_1_540x360.jpg

The findings help explain how about 2 metres of DNA can be neatly packaged in each of our cells, in a space that is about the width of a hair.

Scientists have identified two sets of proteins in cells that work together to keep the strands unknotted, avoiding tangles that would hamper vital biological processes.

Proteins - Organisms - Scientists - Role - DNA

These proteins are found in many organisms, and scientists believe that their role in managing DNA may be common throughout nature.

One family of proteins -- known as SMC -- acts like a belay device used by rock climbers, which passes ropes through a series of loops.

Proteins - Set - TopoII - Tangles - Way

These proteins have been found to work alongside another set, known as TopoII, which was previously thought to help solve tangles, but in a way that was not well understood.

Researchers at the Universities of Edinburgh and Padova in Italy studied the process by creating computer models...
(Excerpt) Read more at: ScienceDaily
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