Top stories: Vaccine durability, the universe’s first molecule, and CRISPR’s powerful cousin

Science | AAAS | 4/19/2019 | Staff
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Vaccines for the flu, mumps, pertussis, meningococcal disease, and yellow fever all lose their effectiveness faster than official immunization recommendations suggest. Now, researchers are ramping up efforts to figure out why some vaccines protect for mere weeks, but others work for life. Insights about vaccine durability from unusually successful inoculations are also sparking scrutiny of existing vaccine booster recommendations.

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The universe’s very first molecule, thought to be created after the big bang, has been detected in space for the first time. Helium hydride, a combination of helium and hydrogen, was spotted some 3000 light-years from Earth by an instrument aboard the airborne Stratospheric Observatory for Infrared Astronomy, a telescope built into a converted 747 jet that flies above the opaque parts of Earth’s atmosphere.

Researchers - Years - Base - Editors - Version

When researchers first reported 3 years ago that they had created base editors, a version of the powerful genome-editing tool CRISPR, excitement swirled around their distinct powers to more subtly alter DNA compared with CRISPR itself. But the weaknesses of base editors have become increasingly apparent, and a new...
(Excerpt) Read more at: Science | AAAS
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