Long-read DNA analysis can give rise to errors

ScienceDaily | 1/22/2019 | Staff
KimmyPoo (Posted by) Level 3
New methods that can read lengthy sections of genetic material -- categorised by a series of letters -- are up to 99.8 per cent accurate, however, in a genome of more than 3 billion letters, this may equate to millions of mistakes in the results.

These errors may falsely indicate that an individual has a genetic difference that heightens their risk of a particular disease.

Researchers - Data - Technologies - Caution - Problems

Researchers say data produced by these technologies should be interpreted with caution, as it may create problems for analysing genetic information from people and animals.

Previously, genetic sequencing technologies were focused on reading short strings of DNA. These sequences would be patched together, which is time consuming and labour intensive.

Approach - Genes - Organisms

This approach is useful for reading individual genes but is inappropriate for entire organisms.

Experts from the...
(Excerpt) Read more at: ScienceDaily
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