Scientists grow 'perfect' human blood vessels in lab in breakthrough for heart disease research

Mail Online | 1/16/2019 | Mark Prigg For
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Scientists have managed to grow 'perfect' human blood vessels in the lab for the first time.

The breakthrough could have a dramatic effect on research into a host of vascular problems, including diabetes.

Researchers - Drugs

It will allow researchers to study and test new drugs far more easily.

'Being able to build human blood vessels as organoids from stem cells is a game changer,' said the study's senior author Josef Penninger, director of the Life Sciences Institute at the University of British Columbia.

Organ - Body - Circulatory - System

'Every single organ in our body is linked with the circulatory system.

'This could potentially allow researchers to unravel the causes and treatments for a variety of vascular diseases, from Alzheimer's disease, cardiovascular diseases, wound healing problems, stroke, cancer and, of course, diabetes.'

Penninger - Colleagues - Method - Blood - Vessel

Penninger and his colleagues developed a method to grow three-dimensional human blood vessel 'organoids' grown in a petri dish.

An organoid is a three-dimensional structure grown from stem cells that mimics an organ and can be used to study aspects of that organ in a petri dish.

Organoids - Stem - Cells - Lab - Structure

These so-called 'vascular organoids' can be cultivated using stem cells in the lab, strikingly mimicking the structure and function of real human blood vessels.

When researchers transplanted the blood vessel organoids into mice, they found that they developed into perfectly functional human blood vessels including arteries and capillaries.

Discovery - Blood - Vessel - Organoids - Stem

The discovery illustrates that it is possible to not only engineer blood vessel organoids from human stem cells in a dish, but also to...
(Excerpt) Read more at: Mail Online
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