Common herbicide compound may save millions of lives

phys.org | 10/4/2018 | Staff
superdudea (Posted by) Level 3
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A chemical compound found in common herbicides could help fight hospital-acquired human fungal pathogenic infections, which claim an estimated two million lives per year.

A team of international researchers led by The University of Queensland has discovered that the chemical chlorimuron ethyl also targets a range of fungal infections that are potentially fatal to humans, particularly people undergoing treatments which place the immune system under stress.

Dr - Luke - Guddat - UQ - School

Dr. Luke Guddat, from UQ's School of Chemistry and Molecular Biosciences, said the finding was very timely, given the growth in drug-resistant infections.

"There are more drug-resistant fungal diseases than ever – posing a major threat to global human health – and new drugs are urgently required to combat these diseases," he said.

Research - Class - Herbicide - Ability - Growth

"Through this research we wanted to see if a specific class of commercial herbicide has the ability to stop the growth of these infections.

"We thought this was a good idea, since plants and fungi have a similar enzyme that these chemicals inhibit, and it turns out we were correct."

Researchers - Families - Compounds - Enzyme - Species

The researchers tested five different families of compounds, to see if they could inhibit a key enzyme from the fungal species, Candida albicans...
(Excerpt) Read more at: phys.org
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