Click For Photo: https://www.sciencedaily.com/images/2018/07/180712100543_1_540x360.jpg
The Drosophila embryonic hindgut first forms as a bilaterally symmetric structure and then rotates 90°counterclockwise as viewed from the posterior to become asymmetric. Before the hindgut rotation, cells in the hindgut tilt leftward and are asymmetric. This structure cannot be superimposed on its mirror image, so this asymmetric structure is called 'cell chirality.'
As cell chirality disappears after the rotation, it was thought that cell chirality was related to this hindgut rotation. Previous studies, however, were performed using fixed samples, so the cellular dynamic mechanism by which cellular chirality was converted into an LR asymmetric organ remained unknown.
Researchers - Kenji - Matsuno - Osaka - University
Researchers led by Kenji Matsuno at Osaka University used live imaging of the Drosophila embryonic hindgut and computer simulations to clarify that a novel cellular behavior called "cell sliding" was important for the LR asymmetric...
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