Researcher discovers mechanisms and epigenetic markers with implications for diseases ranging from cancers to infertility

ScienceDaily | 4/30/2018 | Staff
Stem cell research has applications for treating cancer, heart disease, neurological disorders like Alzheimer's disease, diabetes, and even injuries. These cells can replicate and replace damaged tissue, so understanding their development is important to the future of this work. Epigenetic factors, or environmental factors that affect the way genes are expressed, can also play a large role in cell and tissue development, and no studies have previously looked at the mechanisms at play in germline stem cell development and how epigenetics play a role.

"From genome to phenome as it is called is a very complicated process for different gene networks to create the trait you see in an animal or human. The activity of key genes is the same or similar in common cell types, but the activity of other genes may differ completely among species, especially for the roles of stem cells," explains Dr. Jiuzhou Song, Professor in the Department of Animal and Avian Sciences, College of Agriculture and Natural Resources. "Looking at these mechanisms helps to decode genes, understand complex traits, and develop future treatment plans to better understand animal and human health."

Focus - Study - Cells - Mechanisms - Germ

That was the focus of this study, examining germ cells to clarify mechanisms that factor into germ cell development and gene expression. Specific processes were discovered for individual genes with associations...
(Excerpt) Read more at: ScienceDaily
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